Molecular Pathology is the study of disease and chromosomal abnormalities at the molecular level to aid in diagnosis and therapeutic intervention of disease processes.Molecular pathology seeks to explain why a given genetic change should result in a particular clinical phenotype. We have already reviewed the nature . There are three areas of testing that includes genetics, hematopathology, and infectious disease. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.