Systems biology is the study of biological systems whose behaviour cannot be reduced to the linear sum of their parts’ functions. Systems biology does not necessarily involve large numbers of components or vast datasets, as in genomics or connectomics, but often requires quantitative modelling methods borrowed from physics.   The proposed protocols can resist the intercept-resend, entangle-measure, collusion, collective, and coherent quantum attacks. They have better computation as well as communication costs and no player can get other player’s private input.Systems biology is an approach in biomedical research to understanding the larger picture—be it at the level of the organism, tissue, or cell—by putting its pieces together. It's in stark contrast to decades of reductionist biology, which involves taking the pieces apart.