These squamous cell cancers are often referred to as squamous cell carcinomas of the head and neck. Head and neck cancer is a general term that covers many different types of cancer. Cancers can be beningn and malignant in terms of their localization and traversing to other parts of the body. Head and neck squamous cell carcinoma (HNSCC) develops in the mucous membranes of the mouth, nose, and throat. HNSCC is classified by its location. Head and neck cancer can cause pain or a burning sensation when chewing and swallowing food. Patient  might feel like food is stuck in your throat. Head and neck cancers account for about 4 percent of all cancers in the United States. They affect about 65,000 people a year.Head and neck squamous cell carcinoma (HNSCC) represents a group of tumors arising in the oral cavity, oropharynx, and larynx.