"Sickle cell disease (SCD) may be a group of blood disorders typically inherited from an individual's parents. the foremost common type is understood as red blood cell anemia (SCA). It leads to an abnormality within the oxygen-carrying protein hemoglobin found in red blood cells. This results in a rigid, sickle-like shape under certain circumstances. Problems in red blood cell disease typically begin around 5 to six months aged. variety of health problems may develop, like attacks of pain ("sickle cell crisis"), anemia, swelling within the hands and feet, bacterial infections, and stroke. Long-term pain may develop as people grow old. The typical anticipation within the developed world is 40 to 60 years. Sickle cell disease occurs when an individual inherits two abnormal copies of the β-globin gene that creates hemoglobin, one from each parent.