Shwachman-Diamond disorder is an acquired condition that influences numerous pieces of the body, especially the bone marrow, pancreas, and bones.

The significant capacity of bone marrow is to deliver fresh blood cells. These incorporate red platelets, which convey oxygen to the body's tissues; white platelets, which battle disease; and platelets, which are platelets that are essential for ordinary blood thickening. In Shwachman-Diamond condition, the bone marrow glitches and doesn't make a few or a wide range of white platelets. A deficiency of neutrophils, the most well-known kind of white platelet, causes a condition called neutropenia. The vast majority with Shwachman-Diamond disorder have at any rate intermittent scenes of neutropenia, which makes them progressively helpless against contaminations, frequently including the lungs (pneumonia), ears (otitis media), or skin.