The situation where at a particular area of the body has an inflammation then it is known as septic shock. The major risk related to it is organ failure, in some cases it is multiple organ failure. It simultaneously leads to death. It mainly occurs to kids and old aged people as their immune system is very weak and it can’t cope with the infection. There is another type or class of septic shock and it is known as ischemia. Peer review refers to the work done during the screening of submitted manuscripts and funding applications. This process encourages authors to meet the accepted standards of their discipline and reduces the dissemination of irrelevant findings, unwarranted claims, unacceptable interpretations, and personal views. Publications that have not undergone peer review are likely to be regarded with suspicion by academic scholars and professionals.