Tissue chips are engineered microsystems that represent units of human organs — such as the lung, liver and heart — modeling both structure and function. The chips merge techniques from the computer industry with modern tissue engineering to combine miniature models of living organ tissues on a transparent microchip.4/7 The Organs-on-Chips are crystal clear, flexible polymers about the size of a computer memory stick that contain hollow channels fabricated using computer microchip manufacturing techniques. These channels are lined by living cells and tissues that mimic organ-level physiology.In 2010, Harvard's Wyss Institute, led by Donald Ingber, produced the first successful chip, a lung model. Two years later Ingber's lab was included in a public-private collaboration tasked with creating 10 different human organs-on-chips