Reflex enuresis (RA) was outlined by Hull as stop of wee-wee output from each urinary organ thanks to irritation or trauma to at least one kidney or its channel, or severely painful stimuli to different organs. this is often not a standard conception among urologists or nephrologists albeit it's been projected for quite 0.5 a century. The development has not been totally understood. however intrarenal arterial blood vessel spasm and ureteral spasm have gained wide acceptance because the mechanisms of RA. this review summarized papers printed up to currently on RA, so as to depict the overall profile of the illness and to any elucidate the pathological process of RA. An organization of RA was projected as neurovascular reflex, ureterorenal reflex, radiated renovascular reflex, Reno ureteral reflex, ureter ureteral reflex and radiated ureteral reflex, supported the assumed mechanisms and therefore the stimulus' origins. of these sorts except Reno ureteral reflex had gained supporting proof from animal experiments and/or clinical case reports. RA could be an identification of exclusion, solely being thought of when ruling out common and tangible etiologies like ureteral calculi, acute cannular spacious, excretory organ tube occlusion, hypovolemia, infection, etc. If the identification has been established, treatment set up ought to be directed toward the mechanisms quite the contributory factors. Abnormalities of the involuntary nerve system and inborn system malformations incline individuals to RA. In summary, RA could be a stop of wee-wee production caused by stimuli on urinary organ, channel or different organs, through a mechanism of reflex spasm of intrarenal arterioles or ureters, resulting in acute failure. it's a practical instead of parenchymal illness.