RSA, definite as 2 or additional repeated pregnancy losses, disturbs about 2-3% of girls attaining pregnancy. The experience takes an important emotional, physical and financial toll on patients and their families. Presently accepted testing for uterine anatomic abnormalities, Antiphospholipid antibodies (APA) and karyotypic abnormalities of the oldsters leave about 50% of RSA unexplained. The absence of pure causality and treatment to stop recurrence episodes adds to the load of this diagnosis. Review articles are the summary of current state of understanding on a specific research topic. They analyze or discuss research previously published by scientist and academicians instead of reporting novel research results. review comes within the sort of systematic reviews and literature reviews and are a sort of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the standards . They then compare the results presented in these papers.