Radial nerve entrapment is an uncommon diagnosis that is prone to under-recognition. Compression or entrapment can occur at any location within the course of the nerve distribution, but the most frequent location of entrapment occurs in the proximal forearm. This most common location is typically in proximity to the supinator and often will involve the posterior interosseous nerve branch. The radial nerve arises from C5 to C8 and provides a motor function to the extensors of the forearm, wrist, fingers, and thumb. The superficial radial nerve provides a sensory function to the posterior forearm. Depending on the location of entrapment, a patient may experience pain, numbness, weakness, and overall dysfunction or any combination of these. Radial nerve entrapment is often thought to be a result of overuse but can certainly occur secondary to other causes such as direct trauma, fractures, lacerations, compressive devices, or post-surgical changes. The radial nerve divides into the superficial radial and posterior interosseous nerves at the level of the radiocapitellar joint. The posterior interosseous nerve runs along the radial neck before piercing the supinator muscle, a common site of entrapment.  The nerve further divides into four terminal branches that can typically be compressed at one of four other sites as well.