These articles basically include matter related to protein sequencing. Sequencing is of many types and they are DNA sequencing, RNA sequencing, protein sequencing, etc. but in this article only reports or information related to protein sequencing is present. Protein sequencing is basically used for knowing the structure of biopolymer. The top open access journals are peer reviewed scholarly journals of Next Generation: Sequencing and Application. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in MEDLINE, PUBMED, SCOPUS, COPERNICUS, CAS, EBSCO and ISI. It is expected that applying these new technologies will lead to discovery of a host of novel oncogenes and tumor suppressors, which will have a significant impact in our understanding of tumorigenesis and in the clinical management of cancer patients.