In medicine, a prosthesis (plural: prostheses; from Ancient Greek prosthesis, "addition, application, attachment") or prosthetic implant is an artificial device that replaces a missing body part, which may be lost through trauma, disease, or a condition present at birth (congenital disorder). Prostheses are intended to restore the normal functions of the missing body part. Amputee rehabilitation is primarily coordinated by a physiatrist as part of an inter-disciplinary team consisting of physiatrists, prosthetists, nurses, physical therapists, and occupational therapists. Prostheses can be created by hand or with computer-aided design (CAD), a software interface that helps creators design and analyze the creation with computer-generated 2-D and 3-D graphics as well as analysis and optimization tools. prosthetic joint infections has been successfully publishing quality Research article from many years and looking forward to frame up eminent, outstanding issues with best quality research articles in this year. We request you to kindly submit and publish your paper in this best journal and get global acknowledgment