Patients who cannot be transfused for medical or religious reasons present unique management challenges in the setting of high anticipated intraoperative blood loss.  Patients who cannot be transfused for medical or religious reasons present unique management challenges in the setting of high anticipated intraoperative blood loss. Bloodless surgery is a relatively new discipline within perioperative care with the intent of safely avoiding transfusion while maintaining acceptable patient outcomes. As bloodless surgery becomes increasingly mainstream, we can aspire to see this level of coordinated patient care take root and influence preoperative care more broadly as bloodless procedures evolve in such diverse fields. Review articles are the summary of current state of understanding on a particular research topic.They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications. The concept of "review article" is separate from the concept of peer-reviewed literature. It is possible for a review to be peer-reviewed, and it is possible for a review to be non-peer-reviewed.