Physical chemistry is the study of macroscopic, and particulate phenomena in chemical systems in terms of the principles, practices, and concepts of physics such as motion, energy, force, time, thermodynamics, quantum chemistry, statistical mechanics, analytical dynamics and chemical equilibrium.physical chemistry. Physical chemistry is the branch of chemistry that deals with the physical structure of chemical compounds, the way they react with other matter and the bonds that hold their atoms together. An example of physical chemistry is nitric acid eating through wood