The Median Duration of Response tells you how long your cancer can be expected to respond to the chemotherapy, before the cancer starts growing again. For most cancers where palliative chemotherapy is used, this number ranges from 3-12 months. The longer the response, the longer you can expect to live The notion of professional caring, the building of therapeutic relationships and the practice of nursing as a regulated profession with definable standards include in providing palliative care to patients. Regional Anesthesia is the technique of involving patients' body insensate to surgical stimuli by rendering a small portion. Regional anesthesia compared to general anesthesia. Regional anesthetics get in reducing pain, thereby facilitating surgical procedures. Regional anesthetics comparatively are safer than general or systemic anesthetics; therefore, they are used whenever possible. Ultrasound imaging has become a popular technique to perform regional anesthesia. Regional anesthetics have been associated with less post-operative pain and less nausea. Regional anesthesia is particularly appealing to patients undergoing orthopedic procedures. A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.