An ailment that upsets the supplanting of old bone tissue with new bone tissue. Paget's ailment of bone most generally happens in the pelvis, skull, spine and legs. Hazard factors incorporate expanding age and a family ancestry of the condition. After some time, influenced bones may get delicate and deformed. This condition can be symptomless for a significant stretch of time. At the point when indications do happen, they may incorporate bone disfigurements, broken bones and agony in the influenced territory. Treatment includes drug that decreases the breakdown of bone. that is strangely formed, feeble, and fragile. Paget's sickness frequently influences more established individuals, happening in roughly 2 to 3 percent of the populace beyond 55 years old. Numerous patients with Paget's illness have no side effects at all and are uninformed they have the infection until x-beams are taken for some other explanation. At the point when bone agony and different manifestations are available, they can be identified with the infection itself or to intricacies that emerge from the ailment, for example, joint inflammation, bone distortion, and breaks. As a rule, treatment for Paget's illness includes taking prescriptions to help moderate or postpone the malady. For patients who have complexities, medical procedure might be expected to realign disfigured bones or to help cracks mend.