Occupational skin diseases are ranked among the top five occupational diseases in many countries. Contact Dermatitis due to irritation is inflammation of the skin which results from a contact with an irritant. It has been observed that this type of dermatitis does not require prior sensitization of the immune system. There have been studies to support that past or present atopic dermatitis is a risk factor for this type of dermatitis. Common irritants include detergents, acids, alkalies, oils, organic solvents and reducing agents. Prevention measures include avoidance of the irritant through its removal from the workplace or through technical shielding by the use of potent irritants in closed systems or automation, irritant replacement or removal and personal protection of the workers.Occupational skin diseases can take several forms, including irritant contact dermatitis; allergic contact dermatitis; skin cancers, infections and injuries; and other skin diseases. Contact dermatitis – also known as eczema – is the most commonly reported occupational skin disease. Symptoms include painful and itchy skin, blisters, redness, and swelling.Occupational skin diseases and disorders most often are caused by chemical agents by way of either primary irritants or sensitizers. Primary irritants act directly on a worker’s skin through chemical reactions, while sensitizers – through repeated exposure – can result in allergic reactions. Workers’ skin can be exposed to chemicals through direct contact with a contaminated surface, inhaling aerosols, immersion and splashes.