Nitrogen (N) is a major limiting nutrient to sustain crop yields and quality. As a result, N fertilizer is usually applied in large quantities to increase crop production throughout the world. Application of N fertilizers has increased crop yields and resulted in the achievement of self-sufficiency in food production in many developing countries. Excessive application of N fertilizers beyond crops’ demand, however, has resulted in undesirable consequences of degradation in soil, water, and air quality. These include soil acidification, N leaching in groundwater, and emissions of nitrous oxide (N2O), a potent greenhouse gas that contributes to global warming. Long-term application of ammonia-based N fertilizers, such as urea, has increased soil acidity which rendered to soil infertility where crops fail to respond with further application of N fertilizers. Another problem is the groundwater contamination of nitrate-N (NO3-N) which can be a health hazard to humans and livestock if its concentration goes above 10 mg L−1 in drinking water. The third problem is emissions of N2O gas which is 300 times more powerful than carbon dioxide in terms of global warming potential. This chapter examines the effect of N fertilization on soil and environmental quality and crop yields. The impact factor of an academic journal is a scientometric index that reflects the yearly average number of citations that articles published in the last two years in a given journal received. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factors are often deemed to be more important than those with lower ones.