Myomas are benign, monoclonal tumors of the graceful muscle cells of the myometrium. they're composed of huge amounts of extracellular matrix containing collagen, fibronectin, and proteoglycan. Collagen type I and sort III are abundant, but the collagen fibrils are formed abnormally. The presence of myomas is said with fertility. The presence of submucous myomas decreases fertility, and their removal increases fertility to baseline rates. Neither intramural nor subserosal myomas appear to affect fertility rates, and their removal has not been shown to extend fertility. Myomas in pregnancy can affect myoma growth, hooked in to individual differences in genetics, circulating growth factors, and myoma-localized receptors. However, most myomas don't increase in size during pregnancy. Morover, 5% of myomas degenerates during pregnancy. they're of two types. Clinically significant subserosal and intramural myomas can usually be diagnosed by pelvic examination supported findings of an enlarged, irregularly shaped uterus. However, the optimal selection of patients for medical therapy, noninvasive procedures, or surgery depends on an accurate assessment of the dimensions , number, and position of myomas. The techniques available for confirming the diagnosis of myomas include sonography, saline-infusion sonography, hysteroscopy, and MRI. Transvaginal sonography is that the most readily available and least costly technique and should be helpful for differentiating myomas from other pelvic conditions. Saline-infusion sonography uses saline inserted into the cavity to supply contrast and better define submucous myomas, polyps, endometrial hyperplasia, or carcinoma. resonance imagine is a superb method to guage the dimensions , position, and number of uterine myomas and is that the best modality for exact evaluation of submucous myoma penetration into the myometrium. resonance imaging may differentiate adenomyosis from myomas.