Reflecting on the greater understanding of the many diverse causes of myocardial injury, the international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events—including all subtypes of MI. Myocardial infarction is defined as cardiovascular disease which deals with insufficient blood supply and oxygen to heart, then heart muscle gets damaged. The most common symptom is chest pain, shortness of breath, nausea, vomiting. Myocardial Infarction refers to damage or death of an area of the heart muscle (myocardium) resulting from blocked blood supply to the area. The affected tissue dies, injuring the heart. Symptoms include prolonged, intensive chest pain and a decrease in blood pressure that often causes shock.