Musculoskeletal examination ought to incorporate evaluations of quality and of dynamic and inactive extend of movement and assessment for warmth, delicacy, or swelling of joints. Fractiousness and torment on palpation over a bone or neglect pseudoparalysis may be the 1st clue to osteomyelitis. Bone torment may moreover result from neoplastic invasion of the bone marrow or sickle cell iron deficiency. Unexplained fever, arthralgias, and joint pain may be show with intense rheumatic fever, JIA, Lyme malady, Kawasaki illness, SLE, polyarteritis nodosa, and Behçet disorder. Myalgias happen commonly with viral maladies such as flu, and may be show with rickettsial maladies, polyarteritis nodosa, Takayasu arteritis, and dermatomyositis.