Metabolic syndrome is a cluster of metabolic risk factors that come together in a single individual. These metabolic factors include insulin resistance, hypertension (high blood pressure), cholesterol abnormalities, and an increased risk for blood clotting. Affected individuals are most often overweight or obese. An association between certain metabolic disorders and cardiovascular disease has been known since the 1940s.Metabolic syndrome is considered to be a risk factor for cardiovascular diseases and type 2 diabetes. Insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues. Type 2 diabetes is caused by insulin resistance.Metabolic syndrome is also known as syndrome X, insulin resistance syndrome, or dysmetabolic syndrome. Metabolic syndrome is a group of risk factors that raises your risk for heart disease and other health problems, such as diabetesexternal link icon and stroke.