Meniere’s disease could be a disease of the sense organ, characterized by the test of recurrent vertigo, fluctuating sensorineural deafness, and tinnitus.[1] The relapsing nature of the disease may significantly affect the patients’ quality of life, especially during times of acute symptomatology.[2,3] Vertigo mainly influences the physical dimension, while tinnitus and deafness influence the psychosocial dimension of patients’ lives. Clinical symptoms and audiometric tests are the idea for the diagnosis; however, medical diagnosis is also extremely difficult, since most of the findings are subjective and not specific. Misdiagnosis is, therefore, probable, thus highlighting the good need for objective and reliable testing. The aim of the current study is to review the present knowledge on the benefits and drawbacks of the new diagnostic methods for Meniere’s disease. The importance of accurate diagnosis for primary healthcare systems and also the implications of potential misdiagnoses are discussed. an intensive search of the literature was performed in Medline and other available database sources, using the key words “Meniere’s disease”, “vertigo”, “tinnitus”, “diagnosis”, “electrocochleography”, and “glycerol test”. The key word “Meniere’s disease” was considered primary and was either combined to the opposite key words individually, or employed in groups of three. additionally, reference lists from the retrieved articles were manually searched. Information from electronic links and related books were also included within the analysis of information. Four controlled clinical studies, 16 prospective cohort studies, 10 retrospective cohort studies, 1 cross-sectional study, 2 case reports, 1 written guideline, 6 systematic reviews, and three books met with the defined criteria and were included in study selection.