Membranous nephropathy (MEM-bruh-nus nuh-FROP-uh-thee) occurs when the small blood vessels in the kidney (glomeruli), which filter wastes from the blood, become damaged and thickened. As a result, proteins leak from the damaged blood vessels into the urine (proteinuria)Treatment of membranous nephropathy focuses on addressing the cause of your disease and relieving your symptoms. There is no certain cure. However, up to three out of 10 people with membranous nephropathy have their symptoms completely disappear (remission) after five years without any treatment.

Membranous Nephropathy (MN) affects men twice as often as women and is more common in adults between the ages of 40 and 70. It develops slowly, over a number of years and people may not realise they have the disorder.Apart from rare instances in which more than one family member is affected, membranous nephropathy is not a typical hereditary disease in Mendelian terms. On the other hand, it has long been known that primary membranous nephropathy is associated with certain HLA class II immune response genes.

Membranous glomerulonephritis (MGN) is a specific type of GN. MGN develops when inflammation of your kidney structures causes problems with the functioning of your kidney. MGN is known by other names, including extramembranous glomerulonephritis, membranous nephropathy, and nephritis.