Metabolomics in maternal-fetal medication is as yet an "undeveloped" science. Be that as it may, there is as of now an expanding enthusiasm for metabolome of ordinary and entangled pregnancies, and neonatal results. Tissues utilized for metabolomics cross examinations of pregnant ladies, babies and infants are amniotic liquid, blood, plasma, rope blood, placenta, pee, and vaginal discharges. Every distributed paper feature the solid relationship between's biomarkers found in these tissues and fetal mutations, preterm conveyance, untimely crack of films, gestational diabetes mellitus, preeclampsia, neonatal asphyxia, and hypoxic-ischemic encephalopathy. The point of this survey is to sum up and remark on unique information accessible in applicable distributed works so as to stress the clinical capability of metabolomics in obstetrics in the short term.