Lynch syndrome, also referred to as hereditary non-polyposis colorectal cancer (HNPCC), may be a sort of inherited cancer syndrome related to a genetic predisposition to different cancer types. this suggests people with Lynch syndrome have a better risk of certain sorts of cancer. Cancer begins when normal cells begin to vary and grow out of control, forming a mass called a tumor. A tumor are often benign (non-cancerous) or malignant (cancerous), which suggests it can spread to other parts of the body. A benign tumour means the tumor can grow but won't spread.People who have Lynch syndrome have a significantly increased risk of developing colorectal cancer. there's also an increased risk of developing other sorts of cancers, like endometrial (uterine), stomach, breast, ovarian, small bowel (intestinal), pancreatic, prostate, tract , liver, kidney, and common bile duct cancers.

Lynch syndrome is among the foremost common hereditary cancer syndromes, and estimates suggest as many as 1 in every 300 people could also be carriers of an alteration during a gene related to Lynch syndrome. Clues as to if there's Lynch syndrome during a family include diagnoses of colorectal and/or endometrial carcinoma in multiple relatives on an equivalent side of a family. additionally , cancers related to Lynch syndrome are more likely to be diagnosed at a young age. People with Lynch syndrome also are at an increased risk of developing multiple sorts of cancers during their lifetime. ASCO recommends that tumor testing for Lynch syndrome be performed altogether people diagnosed with colorectal cancer and up to date guidelines recommend tumor testing for all endometrial cancers also