Lipids area unit vital cellular and extracellular molecules. eye area unit essential for cell structure, function, and energy, similarly as organs and body insulation and protection. additionally, lipids metabolites area unit extraordinarily essential for a large vary of cellular communication and metabolism. but defective lipids metabolism is standard to modulate a large vary of chronic diseases like vas, cancer, alternative and several other other genetically defective lipids pathways. Major lipids in human health and diseases could generally be classified as saturated and unsaturated fatty acids, sterols, phospholipids, sphingosine derivatives, and numerous alternative lipids metabolites like eicosanoids. during this special issue, we tend to hope to publish papers outlining the Benicia role of lipids and additionally to specialize in the pathological process of lipid metabolism. we tend to area unit significantly inquisitive about topics covering role of lipids in health and its role within the pathological process of fatness, aging, vas diseases, and cancer. Articles ought to contain some lipids organic chemistry, nutrition, physiology, pathology, material medica, or Materia medica. we tend to invite analyzers to submit original analysis articles similarly as review articles that obtain to deal with a more robust understanding of lipid and connected disorders and its mechanisms similarly as recent advances in lipid research.