Leptospira interrogans is a Gram negative, commit aerobe spirochete, with periplasmic flagella. When seen through a dull field magnifying instrument, it regularly takes after a question mark, and this gives the species its name. It is an individual from the family Leptospira. Some significant pathogenic serovars from this species are Canicola, Icterohaemorrhagiae and Australis. L. interrogans is hard to culture, requiring unique media and expanded hatching periods. L. interrogans contaminates wild and residential creatures, including pet mutts. People are inadvertent hosts. It can make due in unbiased or marginally basic water for 3 months or longer. L. interrogans is typically transmitted to people through contact with contaminated creature pee, either legitimately or in water. It attacks straightforwardly through broken skin and can duplicate in the liver and kidneys. Hazard factors for contamination remember working for sewers, cultivating, and recreational water exercises. Disease is known as leptospirosis, which can be asymptomatic, a mellow vague ailment, or result in death from liver harm and kidney failure.Leptospirosis (Leptospira interrogans) is a spirochete contamination that happens worldwide with the exception of in polar areas. The life form endures best in warm, moist conditions and is generally normal in the tropics and subtropics, with numerous wild and residential creature stores including rodents, mice, mutts, pigs, and dairy cattle . After disease, creatures may shed the living being in the pee for a considerable length of time or even years. Living beings multiply in new water, clammy soil, vegetation, and mud and make due for a considerable length of time to months.Infection in people happens after introduction to creature pee, either by direct contact or, all the more generally, as the consequence of roundabout presentation to sullied mud or water in waterways, lakes, and streams. Contamination is procured through harmed skin or by means of uncovered mucous films of the nose, mouth, or eyes. Sullied drinking water may likewise be a noteworthy wellspring of disease.