Many laboratories contain significant risks, and therefore the prevention of laboratory accidents requires care and constant vigilance. samples of risk factors include high voltages, high and low pressures and temperatures, corrosive and toxic chemicals and chemical vapours, radiation, fire, explosions, and biohazards including infective organisms and their toxins. Measures to guard against laboratory accidents include safety training and enforcement of laboratory safety policies, safety review of experimental designs, the utilization of private protective equipment, and therefore the use of the pairing for particularly risky operations. In many countries, laboratory work is subject by health and safety legislation. In some cases, laboratory activities also can present environmental health risks, for instance, the accidental or deliberate discharge of toxic or infective material from the laboratory into the environment. The Laboratory Safety staff provides guidance and oversight to staff within the following areas; use, storage, and disposal of hazardous materials; the event of specific laboratory safety programs; waste minimization; fume hood evaluations; safety newsletters; and assists with plan reviews associated with laboratory renovations.