Pharmaceutical prescriptions are a significant bit of patient thought all through the world. For masters to adequately consider their patients, steady security must be watched and uncovered from starting testing to common use. This is the universe of pharmacovigilance. The World Health Organization describes pharmacovigilance (PV) as "the science and activities relating to the disclosure, assessment, cognizance and evasion of hostile effects or some other medicine related issue. "Pharmacovigilance begins with clinical fundamentals that give data on the focal points and perils of a medicine. The purpose of pharmacovigilance in clinical investigation is to choose whether the favorable circumstances surpass the risks; in case they do, sedate makers figure out how to get underwriting to publicize the new prescription. The information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. Impact factor plays a major role for the particular journal. Journal with higher impact factor is considered to be more important than other ones.