Inflammation is triggered when innate immune cells detect infection or tissue injury. Surveillance mechanisms involve pattern recognition receptors (PRRs) on the cell surface and in the cytoplasm. Other triggers of inflammation include allergens, which form antibody complexes that stimulate Fc receptors on mast cells. In biology, cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates multiple-cell actions. All cells receive and respond to signals from their surroundings. Cell Signaling is an important facet of biological life. It allows cells to perceive and respond to the extracellular environment allowing development, growth, immunity, etc. Additionally, errors in cell signaling may result in cancer growth, diabetes.