Infectious diseases are caused by infectious organisms. Typically, these are bacteria, viruses, fungi, or worms helminths. Under mundane circumstances, when the immune system of the host is plenarily functional, disease symptoms may not develop. If the host immune system is compromised, or the infectious agent inundates the immune system, an infectious disease ensues. Most infections are caused by bacteria, viruses, protozoa, helminthes, rickettsia, and fungi. Prions are responsible for slow-progressing neurological disorders such as Creutzfeldt-Jakob Disease.With the revelation of penicillins, it appeared as that infectious diseases, in particular bacterial infections, would no longer be a major public health quandary. However, with the development of drug-resistant bacteria, fatal viral diseases such as AVAILS, and rigorous acute respiratory syndrome caused by variants of Corona viruses, this early optimism appears unwarranted. Albeit quarantine is efficacious in controlling the spread of diseases such as SARS and hemorrhagic pyrexias caused by Ebola virus, there is no efficacious treatment yet for many infectious diseases.Emerging infectious diseases is an expression used to describe a number of incipient infectious diseases. Astringent Acute Respiratory Syndrome (SARS) is such an example of an emerging infectious disease, where an astringent variant of Corona virus spread across continents within a matter of weeks. Mad cow disease, a variant of Creutzfeldt-Jakob Disease, is another recherche, but widely publicized, infection caused by prions.To increase the visibility and ease of use of open access scientific and scholarly journals top online publishing journals are indexed in different indexing and archiving services. Indexing provides easy access of the article online. The top online publishing journals publish articles which are cited as references by many authors in their work. Citations are important for a journal to get impact factor. Impact factor is a measure reflecting the average number of citations to recent articles published in the journal. The impact of the journal is influenced by impact factor, the journals with high impact factor are considered more important than those with lower ones. Indexing provides easy access of the article online. The international journals are among the best open access journals in the world, set out to publish the most comprehensive, relevant and reliable information based on the current research and development on a variety of subjects. This information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. Impact factor plays a major role for the particular journal.