Immunotoxicology (here and there condensed as ITOX) is the investigation of the harmfulness of remote substances called xenobiotics and their impacts on the safe framework. Some poisonous specialists that are known to modify the invulnerable framework include: modern synthetics, overwhelming metals, agrochemicals, pharmaceuticals, drugs, bright radiation, air contaminations and some organic materials .The impacts of these immunotoxic substances have been appeared to change both the intrinsic and versatile pieces of the resistant framework. Results of xenobiotics influence the organ at first in contact (frequently the lungs or skin). Some usually observed issues that emerge because of contact with immunotoxic substances are: immunosuppression, touchiness, and autoimmunity.The poison prompted safe brokenness may likewise expand helplessness to cancer.The investigation of immunotoxicology started during the 1970s..