Hiv Therapeutics
In many people who have human immunodeficiency infection (HIV), the resistant framework can't control or fix the contamination. Antiretroviral treatment medications can keep the measure of HIV infection low for quite a while. In any case, this treatment doesn't expel the infection from the body. In by far most of patients antiretroviral treatment likewise won't shield the body from the infection once treatment stops. Analysts need to check whether remedial immunization can help individuals with HIV. Helpful immunization implies offering antibodies to treat a disease that somebody as of now has (HIV, for this situation). It might help the body's invulnerable framework assault the contamination. This investigation will take a gander at various proportions of HIV contamination subsequent to getting either restorative immunization or a fake treatment. Goals: To see whether helpful immunization is protected and can influence how the body reacts to HIV infection. Eligibility:Individuals somewhere in the range of 18 and 65 years old who have HIV and are taking antiretroviral treatment drugs. Design:Participants will be screened with a physical test and clinical history. Blood and pee tests will be collected.During the screening visit and all through the investigation until week 56, members will keep on taking their HIV medications.Participants will be separated into two gatherings. One gathering will have the investigation antibodies. The other will have a placebo.The first investigation immunization or fake treatment will be given in weeks 4, 12, and 36. The second examination immunization or the fake treatment will be given in weeks 24 and 48. Blood tests and different tests will be given at each visit.After the examination visit at week 56, members will stop their HIV drugs until week 72. From weeks 58 through 72, they will come in at regular intervals for study visits; each visit will take around 1 hour to finish. These visits will take a gander at the body s reaction to the immunizations and their HIV viral burden. After week 72, members will re-start their HIV medications.There will be follow-up study visits from weeks 76 to 96, with blood tests and different investigations
Last Updated on: Nov 24, 2024