Human Immunodeficiency Virus is the virus that causes AIDS. There are many clinical trials that are going on in HIV as this is the second most common disease in the world now. Many trials are targeted in developing and under developed countries.

The animal experimental models for HIV/AIDS research are considered to be the most suitable way to evaluate salient aspects of new medicines or vaccine candidates, as they have to be tested for their safety and efficacy. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.