Gastric malignant growth has a significant spot in the overall frequency of disease and disease related passings. It can metastasize to the lymph hubs in the beginning times, and lymph hub metastasis is a significant prognostic factor. Medical procedure is a significant piece of gastric malignancy treatment. A D2 lymphadenectomy is the standard careful treatment for cT1N+ and T2-T4 malignant growths, which are conceivably reparable. As of late, the TNM characterization framework was redesigned, and the edges for gastrectomy and lymphadenectomy were modified. Endoscopic, laparoscopic and automated medicines of gastric malignancy have advanced quickly with improvement of careful instruments and methods, particularly in Eastern nations. Distinctive endoscopic resection methods have been recognized, and these can be partitioned into two primary classes: endoscopic mucosal resection and endoscopic submucosal dismemberment. Negligibly intrusive medical procedure has been accounted for to be sheltered and compelling for early gastric malignancy, and it tends to be effectively applied to cutting edge gastric disease with expanding experience. Cytoreductive medical procedure and hyperthermıc intraperıtoneal chemotherapy were created as a joined treatment methodology from the consequences of exploratory and clinical examinations. Additionally, hyperthermia expands the antitumor action and entrance of chemotherapeutics. Trastuzumab which is a monoclonal immune response communicates with human epidermal development factor (HER) 2 and is identified with gastric carcinoma. The counter tumor component of trastuzumab isn't unmistakably referred to, however instruments, for example, interference of the HER2-intervened cell flagging pathways and cell cycle movement have been accounted for already. H. pylori is engaged with 90% of every single gastric threat and Japanese rules emphatically suggest that all H. pylori contaminations ought to be annihilated paying little heed to the related malady. The TNM organizing framework is the highest quality level for arranging of a wide range of tumors. The profundity of the disease and number of the metastatic lymph hubs are the most significant prognostic components for healing gastric malignant growth medical procedure. Two significant organizing frameworks exist for gastric malignant growth. The principal framework is the Japanese Gastric Carcinoma Classification (JGCC) which depends on the area of the metastatic lymph hub, and the second is the Union Internationale Contre le Cancer/American Joint Committee Cancer (UICC/AJCC) TNM organizing framework, which depends on the quantity of metastatic lymph nodes.The TNM grouping framework was adjusted to the JGCC in 2009 and called the UICC/AJC TNM arranging framework in the seventh release.