A fermenter is designed to provide a controlled and favorable environment for the growth of cells irrespective of their nature either they are bacterial or fungi or plant or animal cells. Few aspects to be considered while we design a fermenter are about its proper aeration and agitation, low power consuming, controlling of operational and fermenter parameters should be provided, should be aseptically operated, sampling facilities should be provided, design should ensure minimal use of labor for operation, cleaning, harvesting and maintaining the fermenter, it should be economical in its manufacture. Various parts which include are large container, agitators and impellers, motor, baffles, spargers, valves, sensors and probes, coolant/steam jackets etc. Based on the type of the cell culture put in use, we can select any of the following fermenter as per the requirements of the process. Either we can select stirred tank fermenters, air-lift fermenters, plug flow reactors, fluidized bed bioreactors, packed-bed bioreactors, bubble column fermenters accordingly to the requirement. High-impact journals are those considered to be highly influential in their respective fields.