Family Hypercholesterolemia Top Open Access Journals
Familial hypercholesterolemia or FH is an inherited defect in how the body recycles LDL (bad) cholesterol. As a consequence, LDL levels in the blood remain very high – in untreated adults, above 190 milligrams per deciliter (mg/dL) of blood.People with FH are essentially born with high LDL cholesterol. Everyone’s cholesterol levels tend to rise with age. But those with FH have LDL levels that start high and go even higher over time.
Familial hypercholesterolemia (FH) is characterized by a genetic disorder characterized by high levels of cholesterol, especially in very high levels of low-density lipoproteins (LDL, "bad s dlec"), and the underlying body biochemistry with FH and their high cholesterol. The types of cholesterol control methods that are sensitive to genz food and statin tablets). However, treatment (including higher doses of statins) is more effective.
FH is classified as familial dyslipidemia type 2. There are five types of familial dyslipidemia (not including subtypes), and each is classified by an altered lipid profile and by a genetic defect. For example, a high LDL (often due to a defect in the LDL receptor) is type 2. Others include defects in the metabolism of chylomicron, the metabolism of triglycerides and the metabolism of others in VLDL and IDL.
Last Updated on: Nov 28, 2024