Research impact has been defined as “the value and benefit associated with using the knowledge produced through research, and being involved in conducting research.”4 Its meaning and measurement differ among groups and individuals. The meaning of impact for funders and policymakers might be conceived of as an influence on policy, health service delivery, and population health outcomes. Academic institutions are more interested in how discipline is represented in the academic milieu. For researchers, the impact might mean the influence of their work on other researchers and practitioners in the field. For clinicians, the focus will be on the effect on daily practice. Family health history (FHH) is a simple yet invaluable tool for the delivery of personal health risk information (see Chapter 26). Reflecting on the complex combination of shared genetic, environmental, and lifestyle factors, a robust FHH can approximate genetic/genomic risk information and integrate it into patient care. FHH assessments identify persons at higher risk for disease, enabling preemptive and preventive steps, including lifestyle changes, health screenings, testing, and early treatment as appropriate. As such, FHH holds tremendous potential for improving preventive healthcare across broad, diverse populations in a personally relevant manner. However, the assessment and integration of FHH information has not been embraced by the healthcare community and remains a largely untapped resource.