Erythroderma or exfoliative dermatitis is peeling of the skin over large areas of the body.

Exfoliative dermatitis, sometimes called erythroderma, is serious but fairly uncommon. Complications are infection, loss of nutrients, and dehydration. The root cause of exfoliative dermatitis or erythroderma is a disorder of the skin cells. Adverse reactions to a variety of drugs could also contribute to massive skin scaling. Severe symptoms of erythroderma or exfoliative dermatitis will be life threatening. Mortality rates are highest in patients with infection, fluid and electrolyte abnormalities, and cardiac failure. The most common causes of death in patients with erythroderma or exfoliative dermatitis are pneumonia, septicemia, and heart failure A journal is a periodical publication intended to further progress of science, usually by reporting new research.