The principle goals of drug development are effectiveness and protection. due to the fact all capsules can harm in addition to help, protection is relative. The difference between the usual powerful dose and the dose that reasons extreme or life-threatening aspect effects is called the margin of safety. Drug safety is the principle issue of medical remedy which can play a major position in deciding which drug ought to take delivery of to a affected person. additionally, considering the concept of advantage danger balance, we found that drugs with a high chance profile must be prevented unless wished.