Drug delivery is that the technique or method of administering a pharmaceutical compound to attain a therapeutic impact in humans or animals. For the treatment of human diseases, nasal and pneumonic routes of drug delivery area unit gaining increasing importance. These routes give promising alternatives to canal drug delivery notably for amide and super molecule medical specialty. For this purpose, many drug delivery systems are developed and area unit being investigated for nasal and pneumonic delivery. These embody liposomes, PR liposomes, microspheres, gels, prodrugs, cyclodextrins, among others. Nanoparticles composed of perishable polymers show assurance in fulfilling the demanding necessities placed on these delivery systems, like ability to be transferred into Associate in Nursing aerosol, stability against forces generated throughout aerosolization, biocompatibility, targeting of specific sites or cell populations within the respiratory organ, unleash of the drug during a planned manner, and degradation among an appropriate amount of your time., slow delivery, targeted delivery area unit different very enticing strategies and are pursued vigorously.