A disease is Associate in nursing abnormality moving a living organism. Diseases square measure usually understood to be medical conditions that involve a organic process related to a particular set of symptoms. Localized diseases have an effect on specific components of the body; disseminated diseases unfold to different components of the body; and general diseases have an effect on the complete body. Every unwellness method has Associate in Nursing origin, or etiology, however some diseases could gift with totally different or confusing symptoms, creating them tough to diagnose or confirm. The physical symptoms of unwellness are also among emotional symptoms, and a few diseases that have an effect on the chemical balances of the system nervous could manifest in physical symptoms. The information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. Impact factor plays a major role for the particular journal. Journal with higher impact factor is considered to be more important than other ones.