Chronic myeloid leukaemia typically affects older adults. It's caused by a chromosome mutation that occurs spontaneously. Doctors aren't sure what causes the mutation. Many people don't develop symptoms until later stages and the diagnosis is only made through routine blood work. When symptoms do occur, they include bleeding easily, feeling run down or tired, weight loss, pale skin and night sweats. Treatments include targeted drugs, stem-cell transplant, chemotherapy and biological therapy. They come from the National Cancer Intelligence Network. Generally for CML more than 70 out of 100 men (more than 70%) and almost 75 out of 100 women (almost 75%) will survive their leukaemia for 5 years or more after they are diagnosed. This is for all ages.  Latest figures show that the 5-year survival rate for all subtypes of leukemia is 61.4 percent. A 5-year survival rate looks at how many people are still alive 5 years after their diagnosis. Leukemia is most common in people aged over 55, with the median age of diagnosis being 66. When hemoglobin is this low, people commonly feel profound fatigue, confusion and short of breath. With good palliative care these symptoms are manageable. A higher stage number means that CLL is impacting more of the body. A higher stage will often shorten a person's life expectancy.