cell signaling is the system that coordinates the cell communications and cellular activities. The vicissitudes occur in cell to environmental conditions and their replication towards the reaction. Cell signaling is of two types they are intracellular signaling and extracellular signaling, if the signaling takes place within the cell is called intracellular signaling, if it occurs outside is called extracellular signaling. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment implement for grading, evaluating, sorting and comparing journals of homogeneous kind. It reflects the average number of citations to recent articles published in science and gregarious science journals in a particular year or period, and is frequently utilized as a proxy for the relative consequentiality of a journal within its field. It is first devised by Eugene Garfield, the progenitor of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the antecedent two years.

Cell signaling is a process through which living cells interact with the cellular environment and neighbouring cells. Cells contain Glycoproteins or Glycolipids as receptors on their plasma membrane which detects the signals. When a complementary ligand (signaling molecule) comes and binds to the receptor, it initiates a chain of reactions within the cell, ultimately leading to a replication.The Journal of Cell Signaling is a peer reviewed journal. This journal offers an open access platform for authors to publish their research. The Journal of cell signaling is an open access journal which mainly fixates on effector systems, such as protein kinases, lipid signaling pathways, cyclic nucleotide signaling processes, NO signaling and ion channels. The engenderment, regulation, degradation and action of second heralds; the structure, regulation, degradation and action of receptors; Guanine nucleotide regulatory proteins; Bio-informatics studies cognate to cell signaling mechanisms; Compartmentalization/compartmentation of signaling systems; Anchor/scaffold signaling proteins; The effect of cellular signaling events on the functioning, magnification and differentiation of cells in mundane and pathological states and withal cellular oncogenes.The Journal of Cell Signaling accepts all types of articles including research, review, case reports, commentaries, hypotheses, meeting reports and short reports. This scientific journal is utilizing Editorial Tracking System for maintaining quality in peer review process. Review processing is performed by the editorial board members of Journal of Cell signaling or by outside experts. Minimum two independent reviewers approbation followed by editor approbation is obligatory for acceptance of any manuscript.