A bio-marker, or organic marker is a measurable indicator of some organic country or situation. Biomarkers are often measured and evaluated to take a look at everyday biological approaches, pathogenic tactics, or pharmacologic responses to a healing intervention.[1] Biomarkers are used in lots of medical fields.Biomarkers used for medication, or precision remedy, are a part of a noticeably new medical toolset. They are classified in three number one ways according to their scientific applications. They are categorized as molecular biomarkers, cellular biomarkers or imaging biomarkers. All three kinds of biomarkers have a clinical function in narrowing or guiding treatment decisions and comply with a sub-categorization of being both predictive, prognostic, or diagnostic.Predictive molecular, cellular, or imaging biomarkers that bypass validation can serve as a way of predicting clinical results. Predictive biomarkers are used to help optimize best remedies, and often suggest the chance of making the most of a specific remedy. For instance, molecular biomarkers situated at the interface of pathology-particular molecular process structure and drug mechanism of action promise taking pictures elements permitting assessment of an character remedy reaction.[2] This offers a twin technique to both seeing traits in retrospective studies and the usage of biomarkers to expect consequences. For instance, in metastatic colorectal most cancers predictive biomarkers can function a way of evaluating and improving affected person survival costs and inside the character case via case scenario, they could function a way of sparing patients from pointless toxicity that arises from most cancers remedy plans