One of the case studies given here suggests the significance of this strategy. The study is based on the use of PLN to encapsulate an entomopathogenic fungus active against pest insects of palm trees. The beads were formed by extrusion and three fungus conidia concentrations and nanolayered silicate concentrations were used. The matrix was evaluated by X-ray powder diffraction and Fourier transform infrared spectroscopy. The characteristics of the products were assessed: percent of encapsulated conidia, size distribution and polydispersity index, swelling index, in vitro ability of the formulation to release conidia, and stability under different storage temperatures. PLN, whose interactions could be visualized by FTIR, proved to be a potential matrix for this fungus because, while composed of natural substances that are nontoxic to the environment, it succeeded in encapsulating high amounts of conidia.