Biocatalysis has been around for a long time. In fact, it was probably the first type of multi-step chemical reaction humans ever carried out, over 9000 years ago. But seeing as the product of that particular reaction was beer, that’s hardly surprising. Lab coat or mammoth hide, scientists never change. What does change is how the pharmaceutical industry uses bio catalysts. While fermentation technology was used in key drug developments in the past, such as the production of penicillin in 1941, for most of the 20th century the industry favored transition metal catalysts and the profitable mining that uncovered them. Using the DNA sequence of known enzymes, it is possible to search for sequences which are similar. If these same sequences are found, it can then be placed into a different organism and then made to see if the sequence does in fact code for an enzyme. Open access is very important part for maintaining substantial standard in publishing and also brings out the best possible scientific novel kind of information. Open Access Publishing may have many open access journals, and renowned Editorial Board members, and highly qualified, expert reviewers.