Bioanalytical strategy advancement is to characterize the plan, working conditions, confinements, and reasonableness of the strategy for its aiming reason and to guarantee that the strategy is optimized for approval. Bioanalytical strategy advancement does not require broad record keeping or notation. However, the support ought to record the changes to methods as well as any issues and their resolutions amid advancement of the bioanalytical strategy to supply a method of reasoning for any changes amid the advancement of the method.