An hypodermic (or auto-injector) can be a medical device designed to deliver a dose of a selected drug. The injectors were initially designed to beat the hesitation associated with self-administration of the needle-based drug delivery device. Most autoinjectors ar one-use, disposable, device syringes. passage routes of drug administration ar sometimes chosen to optimize actual dose of drug delivered, assure high bioavailability, bypass first-pass metabolism or harsh passage environments, still as maximize the speed of onset. Organ (IM) delivery is also preferred to intravenous delivery once initiating intravenous access is hard or insufferable. Medication is also injected intramuscularly using a syringe or associate degree automatic delivery device (autoinjector). This information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. Impact factor plays a major role for the particular journal. Journal with higher impact factor is considered to be more important than other ones.